INTERVAL FEATURE TRANSFORMATION FOR TIME SERIES CLASSIFICATION USING PERCEPTUALLY IMPORTANT POINTS


Quality, Non-clinical and Clinical Considerations for Biosimilar Monoclonal Antibody Development: EU, WHO, USA, Canada, and BRICS-TM Regulatory Guidelines

Objective: The aim was to critically evaluate well-established regulatory agencies mAb biosimilar guidelines for development and marketing authorization about quality, efficacy and safety and compare to BRICS-TM regulations to identify challenges.Materials and Methods: The current valid guidelines of EMA, WHO, USFDA, BGTD/HC, ICH, and BRICS-TM were

read more

Sensitivity and fidelity of DNA microarray improved with integration of Amplified Differential Gene Expression (ADGE)

Abstract Background The ADGE technique is a method designed to magnify the ratios of gene expression before detection.It improves the detection sensitivity to small change of gene Clear Tote Bag expression and requires small amount of starting material.However, the throughput of ADGE is low.We integrated ADGE with DNA microarray (ADGE microarray) a

read more